For non-invasive diagnostics of kids and adults for lactase deficiency (LD) and other forms of lactose intolerance with the use of hydrogen–methane breath testing (HMBT). Applies in gastroenterology, pediatrics, allergology, immunology, and nutrition for identifying all kinds of innate and acquired lactose intolerance, which causes the inability to digest milk products. Along with the examination of a genetically determined decline of lactase activity, HMBT is recognized as the most accurate method of lactose intolerance diagnostics. It is also non-invasive, easy to use, widely available, and well tolerated by kids.

HMBT diagnostics informative indicators with LACTOtest:
  • Sensitivity - 93%
  • Specificity - 91%
  • Accuracy - 92%
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Lactose enters the stomach after ingestion and remains there, unchanged, for up to 30 minutes
2 step image
Then lactose enters the small intestine unchanged, where it undergoes fermentation by the lactase enzyme, which is produced in the small intestine. At the same time, neither hydrogen nor methane is emitted in the exhaled air
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In case of lactase deficiency, lactose first enters the small intestine in an unchanged form, then 90 minutes after ingestion it goes into the large intestine, where it undergoes splitting (fermentation) by the bacteria of the large intestine, with the release of hydrogen and methane, which are absorbed into the blood, and further into the exhaled air