Description
For non-invasive diagnostics of kids and adults for small intestinal bacterial overgrowth (SIBO) with the use of hydrogen–methane breath testing (HMBT).
Applies in gastroenterology, pediatrics, allergology, and immunology for identifying small intestine excessive contamination with pathogenic microflora, which causes bowel dysfunction.
Along with a bacteriological examination of small intestine aspirate, HMBT is recognized as the most accurate method for diagnosing SIBO. It is also non-invasive, easy to use and widely available.
HMBT diagnostics informative indicators with SIBO test:
Applies in gastroenterology, pediatrics, allergology, and immunology for identifying small intestine excessive contamination with pathogenic microflora, which causes bowel dysfunction.
Along with a bacteriological examination of small intestine aspirate, HMBT is recognized as the most accurate method for diagnosing SIBO. It is also non-invasive, easy to use and widely available.
HMBT diagnostics informative indicators with SIBO test:
- Sensitivity - 90%
- Specificity - 96%
- Accuracy - 92%
1
Lactulose (a synthetic disaccharide) enters the stomach after ingestion and stays there for up to 30 minutes unchanged (the human body does not produce enzymes to break down lactulose).
Then lactulose in an unchanged form enters the small intestine, where it stays for 45 to 75 minutes from the moment of taking on the solution
Then lactulose in an unchanged form enters the small intestine, where it stays for 45 to 75 minutes from the moment of taking on the solution
90 minute standard
2
If there is no SIBO, then lactulose enters the large intestine unchanged 90 minutes after the patient takes the solution, where it undergoes splitting (fermentation) by the bacteria of the large intestine with the release of hydrogen and methane, which are absorbed into the blood, further into the exhaled air
45-60 minute SIBR
3
If there is SIBO, then lactulose undergoes splitting (fermentation) already in the small intestine 45-60 minutes after the patient takes the solution by an excess amount of bacteria of the small intestine with the release of hydrogen and methane, which are absorbed into the blood, further into the exhaled air